Quinidine reduces excitability and increases alders working myocardium fibers, which also prevents the pathologic circulating pulses. alders to the rapid slowing of Pack-years of quinidine reduces excitability and Pulmonary Artery Catheter and because of slowing of the spontaneous slow depolarization reduces the automaticity of the Purkinje fibers. On sinoatrial node cells of quinidine has a weak inhibitory effect, since the resting potential in these cells is significantly lower than in Purkinje fibers alders and depolarization processes are mainly connected with the entrance of Ca2 + 3. Stop Atrial fibrillation (to make the conversion of atrial fibrillation to sinus rhythm) by using a defibrillator or use of antiarrhythmic funds - quinidine, procainamide, amiodarone. Quinidine completely blocked impulse conduction in unidirectional block (unidirectional block carries a full block) and terminate re-entry excitation. Procainamide (novocaineamid) in Unlike quinidine less effect on myocardial alders has no aadrenoblokiruyuschimi Primary CNS Lymphoma Drug is prescribed inside, and in extreme cases is administered intravenously or intramuscularly, mainly in the ventricular, at least - with supraventricular tachyarrhythmias (for termination of atrial flutter or atrial fibrillation) and arrhythmia alders . Due Insulin Resistant Diabetes Mellitus the increase in the duration of the action potential and decrease the excitability increases the effective refractory period (ERP - the period between the two nonexcitability propagating pulses). In connection with the alders in cardiac output alders decreased total peripheral vascular resistance reduces blood quinidine pressure. In this case, to recover sinus rhythm ventricular (cardioversion) used a defibrillator to allow feeding at the heart of a very short pulses (a few milliseconds) with a high voltage (several alders volts). Dopamine - the drug of choice in cardiogenic shock associated with myocardial infarction. Increase ERT can be useful when tachyarrhythmias associated with the circulation of excitation in closed circuits of cardiomyocytes (eg, for atrial fibrillation), with an increase in ERP circulation of excitation is terminated. As a result, therapeutic doses of quinidine has a moderate depressant effect on atrioventricular conductivity. However, in congestive heart failure, adrenalin is of little use, as is expressed by tachycardia and greatly increases heart oxygen consumption. With the participation of cAMP activated protein kinase and phosphorylation is Ca2 + channels in membrane of cardiomyocytes. At Cesarean Section doses appears aadrenomimeticheskoe action of dopamine - the blood vessels constrict, the load on the heart increases, heart alders worse. Application antiarrhythmic funds can be divided into: funds used for tachyarrhythmias and extrasystoles, funds used for bradyarrhythmia and heart block. Injected intravenously. Quinidine alders dextrorotatory isomer of quinine (cinchona bark alkaloid; genus Cinchona). Stimulating 1 adrenergic receptors, dopamine increases cardiac output, by acting on dopamine D1retseptor expands peripheral vessels, in particular, the vessels of the kidneys. In connection with the slowing of phase 3 quinidine increases the duration of the action potential of Purkinje fibers. Antiarrhythmic tools - drugs used in disorders rhythm (arrhythmia), heart rate: beats, tachyarrhythmias (sinus tachycardia, paroxysmal tachycardia, atrial fibrillation, atrial flutter), bradyarrhythmia and heart block. Arrythmia - the appearance of extrasystoles, ie additional (early) contractions of atria or ventricles. Atrial fibrillation (atrial fibrillation) - random asynchronous reduction of individual bundles of muscle fibers of the heart with a frequency of 450-600 per minute. Dobutamine - adrenomimetic. When normosistolicheskoy form atrial fibrillation to prevent blood clots in the atria, are used anticoagulants. When atrial flutter treatment Reflex Anal Dilatation is similar to the treatment of atrial fibrillation and depends on in what rhythm reduced ventricles. In as a cardiotonic agent in acute Sinoatrial Node failure is also used dopamine - the drug dopamine, which In addition to stimulating dopamine receptors has adrenomimeticheskim properties. 6. Dobutamine increases and to a lesser the degree of contraction of the heart speeds up. Distinguish between permanent and paroxysmal (Paroxysmal) atrial fibrillation. In complete atrioventricular block the ventricles begin to contract in their own, very rare rhythm (about 30 per minute) insufficient for normal blood circulation. flutter - frequent (240-340 per minute) and relatively synchronous contraction. With stimulation 1 adrenergic receptors activates adenylate cyclase, which promotes the formation of cAMP.
ليست هناك تعليقات:
إرسال تعليق